Does DHT affect transplanted hair?

One of the most frequently asked questions in Google searches is whether DHT affects transplanted hair. In this article, we will explore the relationship between DHT and transplanted hair based on commonly searched questions and discuss what can be done to maintain a full hair appearance after transplantation.

Understanding DHT and Hair Loss

As is well known, hair loss, particularly male pattern baldness (androgenetic alopecia), is triggered by the hormone dihydrotestosterone (DHT). Many individuals who undergo hair transplantation wonder whether the transplanted hair is not prone to DHT.

The Role of DHT in Hair Miniaturization

DHT is a derivative of testosterone and is responsible for shrinking hair follicles in individuals genetically predisposed to androgenetic alopecia. This process, known as miniaturization, causes hair to thin and eventually fall out, particularly affecting the crown and frontal regions of the scalp.

How Testosterone Converts to DHT

The conversion of testosterone to DHT is carried out by the enzyme 5-alpha reductase:

• Testosterone Production: Primarily produced by the testes and adrenal glands.

• 5-Alpha Reductase Enzyme: Converts testosterone into a more potent androgen, dihydrotestosterone (DHT).

• Effects of DHT: DHT binds to androgen receptors in hair follicles, initiating the miniaturization process, causing follicles to shrink, hair strands to thin, and eventually leading to hair loss.

To prevent this transformation, 5-alpha reductase inhibitors such as Finasteride can be used to lower DHT levels and slow hair loss.

The Resistance of Transplanted Hair to DHT

During hair transplantation, follicles are typically harvested from the donor area, which is usually the back and sides of the scalp. Hair follicles that are not affected by DHT in many males are those in the back and sides of the scalp. These areas often contain hair follicles that are naturally resistant to DHT. Because of this, transplanted hair remains resistant to DHT even after being implanted in the recipient area, reducing the risk of further hair loss.

In hair transplant procedure, follicles from the donor area that are naturally resistant to DHT. (Photo: EstePera Clinic)

Embryonically, the scalp originates from two different sources: the upper part comes from a different origin than the back and sides of the head. Due to this genetic difference, the ability to produce 5-alpha reductase and respond to DHT varies. Not all follicles are negatively affected by DHT; for example, facial hair in men thickens under its influence.

Can DHT Cause Further Hair Loss?

While transplanted hair is resistant to DHT, the surrounding natural, non-transplanted hair remains vulnerable to its effects. This means that, over time, you may continue to lose native hair, potentially leading to an unbalanced hair appearance. To prevent this, many hair restoration experts recommend the following DHT-blocking treatments:

• Finasteride (Propecia): A prescription medication classified as a 5-alpha reductase inhibitor. It is used to lower DHT levels and slow down hair loss.

• Minoxidil (Rogaine): A topical solution that stimulates hair growth, with more gradual and moderate effects. It helps promote hair growth and preserve natural hair.

• Low-Level Laser Therapy (LLLT): A non-invasive treatment that stimulates hair follicles to support hair growth. Using a low-level diode laser that emits infrared light, it targets the scalp for about 15 minutes to encourage hair growth.

• Platelet-Rich Plasma (PRP) Therapy: PRP stands for "platelet-rich plasma." It is a treatment that uses the patient's own blood plasma to support hair growth.

Long-Term Care for Transplanted Hair

To ensure the longevity of a hair transplant, consider the following steps:

• Follow Post-Transplant Care Instructions: Proper hair care and avoiding aggressive treatments will help preserve transplanted hair.

• Use DHT Blockers: With a doctor's guidance, medications such as Finasteride can help prevent hair loss.

• Maintain a Healthy Lifestyle: A balanced diet, stress management, and good hair hygiene contribute to overall hair health.

Hair transplant provides permanent and natural results. (Photo: EstePera Clinic)

Does DHT Affect Transplanted Hair and How to Protect Transplanted Hair from DHT?

In conclusion, while DHT plays a significant role in hair loss, transplanted hair follicles are generally resistant to its effects due to their origin from areas less susceptible to DHT. However, non-transplanted natural hair remains vulnerable to DHT, which could lead to ongoing hair loss and an imbalanced appearance. To maintain the results of a hair transplant and prevent further hair loss, it is crucial to consider DHT-blocking treatments such as Finasteride, Minoxidil, and other therapies like Low-Level Laser Therapy and Platelet-Rich Plasma. A healthy lifestyle, proper post-transplant care, and consistent use of DHT inhibitors can help ensure long-term success and a fuller, more balanced head of hair.